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MISSION
Advancing spinal cord regeneration with innovative biomaterial scaffolds.
Spinal Cord Injuries
The spinal cord, an information superhighway extending from the brain, connects your body and enables sensation and movement. Thousands of nerve fibers transmit vital signals, making spinal cord injuries profoundly impactful by impairing movement and sensation.
The Challenge of Regeneration
The spinal cord has a limited ability to repair itself. A disruptive traumatic event prevents effective healing and recovery. When the protective barrier is breached, it creates a toxic environment that hinders nerve fiber regrowth. These nerve fibers can't regenerate and eventually die, forming a cavity at the injury site.
Breakthrough in Nerve Regeneration
Fatiha Nothias-Chahir's team at the Institut de Biologie Paris-Seine has developed a chitosan-based biomaterial. This fragmented hydrogel reduces cavity formation and promotes nerve fiber regrowth in rats. It can be injected immediately after trauma or later with impressive results in terms of neurological recovery.
Why is Medjeduse approach different ?
Medjeduse tackles spinal cord injuries at their source by supporting and enhance the natural tissue repair process. Unlike exoskeletons or neuromodulation, which merely address symptoms, i.e. lack of mobility and sensation.
Our chitosan-based biomaterial promote spinal cord tissue repair by guiding neurite elongation and outgrowth in order for nerve fibers to reconnect across larger distances. Reconnection allows proper signal transmission.